Description
Product Characteristics:
Aliases: AHH antibody, AHRR antibody, Aryl hydrocarbon hydroxylase antibody, CP11 antibody, CP1A1_HUMAN antibody, CYP 1 antibody, CYP1 antibody, cyp1a1 antibody, CYPIA1 antibody, Cytochrome P1 450 dioxin inducible antibody, Cytochrome P1-450 antibody, Cytochrome P450 1A1 antibody, Cytochrome P450 family 1 subfamily A polypeptide 1 antibody, Cytochrome P450 form 6 antibody, Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1 antibody, Cytochrome P450-C antibody, Cytochrome P450-P1 antibody, Flavoprotein-linked monooxygenase antibody, Microsomal monooxygenase antibody, P1 450 antibody, P450 C antibody, P450 form 6 antibody, P450 P1 antibody, P450DX antibody, Xenobiotic monooxygenase antibody
Target Information: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]